Phenolic constituents from the roots of Alangium chinense
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- 作者：Yan Zhang ; Yun-Bao Liu ; Yong Li ; Shuang-Gang Ma ; Li Li ; Jing Qu ; Dan Zhang ; Jian-Dong Jiang ; Shi-Shan Yu ; yushishan@imm.ac.cn
- 关键词：Phenolics ; Alangium chinense ; Antiviral ; Coxsackie virus B3 ; Antioxidant
- 刊名：Chinese Chemical Letters
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：28
- 期：1
- 页码：32-36
- 全文大小：374 K
- 卷排序：28
文摘
Three new phenolics (1–3) and twenty-eight known compounds (4–31) were isolated from an ethanolic extract of roots of Alangium chinense. Compound 11 exhibited antiviral activity against Coxsackie virus B3 with IC50 values of 16.89 μmol/L. Compounds 1, 10–17, 19–21, and 23 showed strong antioxidant activity against Fe2+-cysteine-induced rat liver microsomal lipid peroxidation, with IC50 values of 0.14–8.18 μmol/L.