Synthesis of carbohydrate-based azamacrocycles by Richman–Atkins cyclisation

详细信息    查看全文

• 作者：Andreas Rathjens^a ; Joachim Thiem ; ^a ; ^{thiem@chemie.uni-hamburg.de}
• 关键词：Aza-macrocycles ; Tethered disaccharides ; Carbohydrates ; Cyclisations
• 刊名：Comptes Rendus Chimie
• 出版年：2011
• 出版时间：February-March 2011
• 年：2011
• 卷：14
• 期：2-3
• 页码：286-300
• 全文大小：519 K

文摘

Symmetrical nitrogen containing ring structures with two or four glucose units were easily obtained from accessible monosaccharide building units. Various tetherings via 4,4’- and 6,6’-positions lead to a variety of precursors which were transformed successively employing different bridging units by Richman–Atkins cyclisation to result in defined glycophane coronands.