The p53-like Protein CEP-1 Is Required for Meiotic Fidelity in C. elegans
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- 作者：Abigail-Rachele F. Mateo1 ; 2 ; Zebulin Kessler3 ; Anita Kristine Jolliffe1 ; 2 ; Olivia McGovern3 ; Bin Yu2 ; Alissa Nicolucci2 ; Judith L. Yanowitz3 ; yanowitzjl@mwri.magee.edu" class="auth_mail" title="E-mail the corresponding author ; W. Brent Derry1 ; 2 ; brent.derry@sickkids.ca" class="auth_mail" title="E-mail the corresponding author
- 刊名：Current Biology
- 出版年：2016
- 出版时间：9 May 2016
- 年：2016
- 卷：26
- 期：9
- 页码：1148-1158
- 全文大小：3420 K
文摘
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CEP-1 cooperates with HIM-5 to ensure meiotic crossover formation
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CEP-1 and HIM-5 promote induction of programmed double-strand breaks
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CEP-1 and HIM-5 ensure DSB repair fidelity by antagonizing NHEJ activity