Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property
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- 作者：Hyung Eun Leea ; c ; Se Jin Jeona ; c ; Byeol Ryua ; c ; Se Jin Parka ; c ; Sang Yoon Koa ; c ; Younghwan Leea ; c ; Eunji Kima ; c ; Sunhee Leea ; c ; Haneul Kima ; c ; Dae Sik Janga ; c ; dsjang@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Jong Hoon Ryua ; b ; c ; jhryu63@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Swertisin ; Memory impairment ; Adenosine ; Alzheimer&rsquo ; s disease
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 June 2016
- 年：2016
- 卷：306
- 期：Complete
- 页码：137-145
- 全文大小：1555 K
文摘
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Swertisin is effective in memory improvement both in normal and impairment model.
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Ameliorating effect of swertisin is from adenosine A1 receptor antagonistic property.
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Swertisin increased the phosphorylation levels of PKA and CREB.