A retrospective study compared the average BTX dose injected in equal doses to the thyroarytenoid (TA) muscles of 51 patients with ADSD with 52 patients with EVT.
Those with ADSD received significantly higher total doses (6.80聽卤聽2.79 units) compared with those with EVT (5.02聽卤聽1.65 units). Dose at time of first injection, age at time of first injection, gender, year of first injection, and average time between injections were included in multivariate analysis but did not interact with total average dose findings.
Patients with ADSD may need relatively higher doses of BTX injections to bilateral TA muscles compared with patients with EVT.