Correlation between nerve growth factor and tissue expression of IL-17 in leprosy
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- 作者：Tinara Leila de Sousa Aarã ; oa ; Jorge Rodrigues de Sousab ; Beatriz Santos Botelhoa ; Hellen Thais Fuziib ; Juarez Antonio Simõ ; es Quaresmaa ; b ; juarez@pesquisador.cnpq.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Nerve grown factor ; IL-17 ; Cytokines ; Immunopathology
- 刊名：Microbial Pathogenesis
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：90
- 期：Complete
- 页码：64-68
- 全文大小：2399 K
文摘
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Leprosy is a serious public health problem in peripheral and developing countries.
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New cytokines profiles may be involved in the inflammatory response to M. leprae.
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Sensory deficits may be involved in the balance of pro-inflammatory cytokines and regeneration factors.
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IL-17 stimulating an inflammatory response and negatively regulates the action of NGF and NGFR.