Langerhans cells (CD1a and CD207), dermal dendrocytes (FXIIIa) and plasmacytoid dendritic cells (CD123) in skin lesions of leprosy patients
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- 作者：Kelly Emi Hiraia ; Tinara Leila de Sousa Aarã ; oa ; Luciana Mota Silvaa ; Jorge Rodrigues de Sousab ; Juarez de Souzaa ; Leonidas Braga Dias Jr.a ; Francisca Regina Oliveira Carneirob ; Hellen Thais Fuziib ; Juarez Antonio Simõ ; es Quaresmaa ; b ; juarez@pesquisador.cnpq.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dendritic cells ; Immunology ; Immunopathology ; Mycobacterium leprae
- 刊名：Microbial Pathogenesis
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：91
- 期：Complete
- 页码：18-25
- 全文大小：3488 K
文摘
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Mycobacterium leprae infections varies widely and depends on the pattern of the host immune response.
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Dendritic cells play an important role in the activation of the innate and adaptive immune system.
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The analysis of dendritic cells was done by immunohistochemistry.
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Results indicate the existence of a larger number of dendritic cells in tuberculoid leprosy.
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Dendritic cells favoring an efficient immune response to M. leprae.