Can early ultrasound reduce the gestational age at abortion for fetal anomalies?

详细信息    查看全文

• 作者：Stephen T. Chasen ; ^{stchasen@med.cornell.edu} ; Robin B. Kalish
• 关键词：Abortion ; Fetal anomalies ; Ultrasound ; Prenatal diagnosis
• 刊名：Contraception
• 出版年：2013
• 出版时间：January, 2013
• 年：2013
• 卷：87
• 期：1
• 页码：63-66
• 全文大小：102 K

文摘

Background

A significant proportion of second-trimester abortions are done for fetal anomalies. Our objective was to evaluate the impact of ultrasound at < 14 weeks on the gestational age at abortion for structural fetal abnormalities.

Study Design

Retrospective review identified all patients undergoing abortion following sonographic diagnosis of structural fetal anomalies at a single institution from 2004-2011. First-trimester ultrasound findings were reviewed, and abnormalities were categorized as ¡°diagnostic¡± or ¡°nondiagnostic.¡± Chi-square analysis and Mann-Whitney U test were used for statistical comparison.

Results

One hundred thirty-two patients who underwent abortion due to structural fetal abnormalities were included, 109 of whom underwent ultrasound at 11-13 weeks. In those scanned at < 14 weeks, there were diagnostic findings in 36 cases (33.0 % ) and abnormal nuchal translucency or other nondiagnostic finding leading to early second-trimester ultrasound in 16 cases (14.7 % ). In those scanned at < 14 weeks, median gestational age at abortion was earlier compared to those who underwent initial anatomic evaluation in the second trimester, 19 weeks (13.5-21) versus 21 weeks (19-22), p=.001.

Conclusion

Ultrasound at < 14 weeks was associated with an earlier gestational age at abortion in pregnancies with structural fetal abnormalities.