Medical factors that predict quality of life for young adults with congenital heart disease: What matters most?

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• 作者：Jamie L. Jackson^a ; ^b ; ¹ ; ^{jamie.jackson2@nationwidechildrens.org" class="auth_mail" title="E-mail the corresponding author} ; Lauren Hassen^c ; Gina M. Gerardo^a ; ¹ ; Kathryn Vannatta^a ; ^b ; ¹ ; Curt J. Daniels^d ; ^e ; ¹
• 关键词：Congenital heart defects ; Quality of life
• 刊名：International Journal of Cardiology
• 出版年：2016
• 出版时间：1 January 2016
• 年：2016
• 卷：202
• 期：Complete
• 页码：804-809
• 全文大小：247 K

文摘

Identify demographic and medical status indicators that account for variability in physical and emotional health-related quality of life (QoL) among young adults with congenital heart disease (CHD) as compared to traditional lesion severity categories.

Methods

Cross-sectional study of 218 young adult survivors of CHD (mean = 25.7, SD = 7.1 years). Participants were recruited from pediatric and adult CHD clinics at a pediatric and an adult hospital. Stepwise linear regression examined the unique contribution of demographic (age; sex; estimated income) and medical status indicators (comorbid conditions; treatment modality; ventricular function/functional capacity) on QoL compared to traditional lesion severity categories (simple; moderate; complex).

Results

Lesion severity category accounted for a small portion of the variance in physical QoL (3%), but was not associated with emotional QoL. Lesion severity did not significantly contribute to the variability in physical QoL once other variables were entered. Having an estimated income of ≤$30,000, taking more than one cardiac-related medication, and having a New York Heart Association (NYHA) functional class designation > I was associated with poorer physical QoL and explained 23% of the variability. NYHA class was the only variable that explained a unique proportion of variance (7%) in emotional QoL, and having a NYHA class designation > I was associated with greater risk for poorer emotional functioning.

Conclusions

Findings suggested that several indicators readily available to treatment teams may provide important information about the risk for poor patient-reported outcomes of physical and emotional QoL among CHD survivors.