Soluble form of the ST2 gene product exhibits growth promoting activity in NIH-3T3 cells
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- 作者：Shin-ichi Tominaga ; shintomi@jichi.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Satoshi Ohta ; Kenji Tago
- 关键词：bp ; base pairs ; cDNA ; complementary DNA ; DMEM ; Dulbecco&rsquo ; s Modified Eagle&rsquo ; s Medium ; EDTA ; ethylenediaminetetraacetic acid ; ELISA ; enzyme-linked immunosorbent assay ; FBS ; fetal bovine serum ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; RT-PCR ; reverse transcription-polymerase chain reaction ; S.D. ; standard deviation ; SDS-PAGE ; sodium dodecylsulfate-polyacrylamide gel electrophoresis ; shRNA ; short hairpin RNA
- 刊名：Biochemistry and Biophysics Reports
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：5
- 期：Complete
- 页码：8-15
- 全文大小：1184 K
文摘
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Soluble ST2 enhanced cell proliferation of NIH-3T3 cells.
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Reduction of the ST2 gene products highly deteriorated cell growth of NIH-3T3 cells.
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Cell proliferation was recovered with supplementation of soluble ST2, but not ST2L.
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Positive feedback system of ST2 on cell proliferation is of great interest.