Haemodynamic effects of intravenous quinaprilat in comparison to sodium nitroprusside in patients with chronic heart failure
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- 作者：Arne G. Kieback ; Andrea Grohmann ; Gert Baumann ; Stephan B. Felix
- 关键词：Intravenous ACE-inhibitor ; Quinaprilat ; Sodium nitroprusside ; Chronic heart failure ; Haemodynamics
- 刊名：International Journal of Cardiology
- 出版年：2007
- 出版时间：14 September 2007
- 年：2007
- 卷：121
- 期：1
- 页码：102-104
- 全文大小：157 K
文摘
We compared the haemodynamic effects of intravenous boluses of the ACE inhibitor quinaprilat with an intravenous infusion of sodium nitroprusside in 23 patients with chronic heart failure (NYHA Class III or IV). At the highest drug doses, sodium nitroprusside significantly increased stroke volume index (+ 6.63 ml/m2, p = 0.045), whereas quinaprilat induced only a minor increase (+ 1.79 ml/m2, n.s.).