Comparing Outcomes with Bone Marrow or Peripheral Blood Stem Cells as Graft Source for Matched Sibling Transplants in Severe Aplastic Anemia across Different Economic Regions
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- 作者：Rajat Kumar1 ; rkumar@cancercare.mb.ca" class="auth_mail" title="E-mail the corresponding author ; Fumihiko Kimura2 ; Kwang Woo Ahn3 ; Zhen-Huan Hu3 ; Yachiyo Kuwatsuka3 ; 4 ; John P. Klein3 ; Marcelo Pasquini3 ; Koichi Miyamura5 ; Koji Kato6 ; Ayami Yoshimi7 ; Yoshihiro Inamoto8 ; Tatsuo Ichinohe9 ; William Allen Wood Jr.10 ; Baldeep Wirk11 ; Matthew Seftel1 ; Philip Rowlings12 ; David I. Marks13 ; Kirk R. Schultz14 ; Vikas Gupta15 ; Laurence Dedeken16 ; Biju George17 ; Jean-Yves Cahn18 ; Jeff Szer19 ; Jong Wook Lee20 ; Aloysius Y.L. Ho21 ; Anders Fasth22 ; Theresa Hahn23 ; Nandita Khera24 ; Jignesh Dalal25 ; Carmem Bonfim26 ; Mahmoud Aljurf27 ; Yoshiko Atsuta28 ; Wael Saber3
- 关键词：Aplastic anemia ; Hematopoietic cell transplantation ; Graft source ; Economic regions
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：22
- 期：5
- 页码：932-940
- 全文大小：1039 K
文摘
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Overall survival was better with bone marrow as graft source in sibling transplants for aplastic anemia.
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Chronic graft-versus-host disease was worse with peripheral blood stem cells as graft source.
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In non–high-income countries, there was no significant survival difference between the 2 graft sources.
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Analysis of registry data should cater to variations in outcomes in different economic regions.