Bmp4 Promotes a Brown to White-like Adipocyte Shift

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• 作者：Salvatore Modica¹ ; Leon G. Straub¹ ; Miroslav Balaz¹ ; Wenfei Sun¹ ; Lukas Varga² ; ³ ; Patrik Stefanicka³ ; Milan Profant³ ; Eric Simon⁶ ; Heike Neubauer⁵ ; Barbara Ukropcova² ; ⁴ ; Jozef Ukropec² ; Christian Wolfrum¹ ; ⁷ ; ^{christian-wolfrum@ethz.ch" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Cell Reports
• 出版年：2016
• 出版时间：23 August 2016
• 年：2016
• 卷：16
• 期：8
• 页码：2243-2258
• 全文大小：5445 K

文摘

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d="p0010">Bmp4 promotes differentiation of brown pre-adipocytes into white-like adipocytes

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d="p0015">Bmp4 blunts the activity of mature brown adipocytes

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d="p0020">Ectopic expression of Bmp4 in brown adipose tissue reduces energy expenditure

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d="p0025">Obese type 2 diabetic subjects have higher levels of circulating BMP4

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