Von Willebrand factor expression in endometrial endothelial cells in women with menorrhagia

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• 作者：Umber Agarwal ; Soha El Sheikh ; Ashwini Kulkarni ; Donna Baff ; Rezan A. Kadir
• 刊名：Fertility and Sterility
• 出版年：2010
• 出版时间：November 2010
• 年：2010
• 卷：94
• 期：6
• 页码：2335-2337
• 全文大小：603 K

文摘

This prospective study assessed von Willebrand factor (VWF) expression in the endometrium using immunohistochemical staining in women with menorrhagia with or without von Willebrand disease (VWD) compared with a control group of women with normal menstrual loss. Endometrial VWF expression is significantly lower in women with VWD, which may play a local underlying role in pathogenesis of menorrhagia in these women.