Atrial fibrillation, CHA2DS2-VASc score, antithrombotics and risk of non-traffic-, non-cancer-related bone fractures: A population-based cohort study
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- 作者：Hui-Chin Laia ; b ; c ; d ; 1 ; Wu-Chien Chiene ; 1 ; Chi-Hsiang Chungf ; Wen-Lieng Leea ; b ; Tsu-Juey Wua ; b ; Kuo-Yang Wanga ; c ; Chia-Ning Liua ; Tsun-Jui Liua ; b ; c ; d ; trliu@vghtc.gov.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Atrial fibrillation ; Fracture ; Osteoporosis ; Antiplatelet ; Anticoagulant ; CHA2DS2-VASc
- 刊名：European Journal of Internal Medicine
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：26
- 期：10
- 页码：798-806
- 全文大小：640 K
文摘
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Patients with atrial fibrillation (AF) are more prone to accidental bone fractures.
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Vulnerable bones include those constituting neck/trunk and lower limbs.
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Risk factors include female, age, previous stroke, and higher CHA2DS2-VASc score.
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Anticoagulant but not antiplatelet agents can reduce the incidence of fracture.
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Yet only patients with higher CHA2DS2-VASc scores or drug compliance get benefits.