Pharmacokinetic comparison of fast-disintegrating and conventional tablet formulations of risperidone in healthy volunteers
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- 作者：van Schaick ; Erno A. ; Lechat ; Philippe ; Remmerie ; Bart M.M. ; Ko ; Grant ; Lasseter ; Kenneth C. ; et. al.
- 关键词：risperidone ; fast-disintegrating tablet ; pharmacokinetics ; healthy volunteers ; bioequivalence
- 刊名：Clinical Therapeutics
- 出版年：2003
- 出版时间：June, 2003
- 年：2003
- 卷：25
- 期：6
- 页码：1687-1699
- 全文大小：848 K
文摘
Background: Difficulties with and resistance to tablet-taking are common in all patient groups and can exacerbate compliance problems and undermine treatment efficacy. In recent years, rapidly dissolving oral drug formulations have been developed to overcome problems related to swallowing difficulties.