Structure of a Eukaryotic RNase III Postcleavage Complex Reveals a Double-Ruler Mechanism for Substrate Selection
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- 作者：Yu-He Liang1 ; Mathieu Lavoie2 ; Marc-Andre Comeau2 ; Sherif Abou Elela2 ; sherif.abou.elela@usherbrooke.ca" class="auth_mail ; Xinhua Ji1 ; jix@mail.nih.gov" class="auth_mail
- 刊名：Molecular Cell
- 出版年：8 May 2014
- 年：2014
- 卷：54
- 期：3
- 页码：431-444
- 全文大小：6207 K
文摘
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The structure of yeast RNase III (Rnt1p) postcleavage complex is determined
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The substrate-binding mode of Rnt1p is distinct from that of bacterial RNase III
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An RNA-binding motif of Rnt1p functions as a guanine-specific clamp
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Rnt1p uses an unusual double-ruler mechanism for substrate selection