• 作者：Sergio Gamaza-Chuliá ; n^a ; ^{gamaza80@hotmail.com} ; Enrique Dí ; az-Retamino^a ; Adriana Ferná ; ndez-Rodrí ; guez^b ; Alberto Girá ; ldez-Valpuesta^a ; Francisco J. Camacho-Jurado^a ; Ver&#243 ; nica Escolar-Camas^a ; Manuel Sancho-Jald&#243 ; n^a ; Rafael Vá ; zquez-Garcí ; a^a
• 关键词：Endocarditis infecciosa ; Pronó ; stico ; Mortalidad
• 刊名：Cardiocore
• 出版年：2010
• 出版时间：October-December 2010
• 年：2010
• 卷：45
• 期：4
• 页码：160-164
• 全文大小：209 K

Objectives

To analyse the clinical, epidemiological profile and prognosis of infective endocarditis in a tertiary hospital.

Methods

A retrospective study of infective endocarditis was performed between 2004 and 2009. The main end-points were death due to infective endocarditis and the composite one of death and need of surgical repair.

Results

Sixty four patients with infective endocarditis were included (39 % women), with 45 months of follow-up. Fifty six percent of the infective endocarditis occurred due to prosthetic valves. The most common isolated organisms were S.Aureus (22 % ), and coagulase-negative Staphylococcus (16 % ). Twenty five percent of patients died during the follow-up (81 % at hospital admission), and 64 % reached the composite end-point. Only Diabetes Mellitus and negative gram bacilli infection were associated with mortality (P<0.05).

Conclusions

There have been changes in clinical, epidemiological and microbiological profile in infective endocarditis in recent years. Despite the improvement in diagnostic and therapeutic process, the morbidity-mortality in this disease is still very high.