Antileukemic activity of an arsenomolybdate in the human HL-60 and U937 leukemia cells

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• 作者：Chunyan Li^a ; Hongqian Cao^a ; Jiaheng Sun^a ; Rui Tian^a ; Dongbei Li^b ; Yanfei Qi^a ; ^{qiyanfei@jlu.edu.cn} ; Wei Yang^b ; ^{ywei@jlu.edu.cn} ; Juan Li^a
• 关键词：Acute promyelocytic leukemia ; Polyoxometalates ; Arsenomolybdate ; Apoptosis
• 刊名：Journal of Inorganic Biochemistry
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：168
• 期：Complete
• 页码：67-75
• 全文大小：1646 K
• 卷排序：168

文摘

Arsenomolybdate-induced apoptosis in leukemia cells via caspase-3 regulatory protein Arsenomolybdate-induced apoptosis in leukemia cells via the bcl-2 regulatory protein Arsenomolybdate arrests the leukemic cells in the G1 phase. The main quenching mechanism for arsenomolybdate and human serum albumin was static quenching.