Reliability of manual and semi-automated measurements of nuchal translucency by experienced operators
详细信息    查看全文
文摘

Objective

To compare intra-/inter-operator reliability of manual and semi-automated NT measurement by experienced operators.

Methods

Images of 103 fetuses at 11 to 13 + 6 weeks were selected. Two operators performed NT measurement independently 3 times each using both manual and semi-automated methods. Intraoperator reliability of the methods was evaluated using ICCs; interoperator reliability was assessed via correlation between the means of the 3 measurements of each operator. Agreement between the 2 methods was evaluated via Bland-Altman plot.

Results

ICCs for the manual method were 0.80 (95 % CI, 0.73-0.85) for operator 1 and 0.82 (95 % CI, 0.76-0.87) for operator 2; ICCs for the semi-automated method were 0.80 (95 % CI, 0.74-0.85) for operator 1 and 0.82 (95 % CI, 0.76-0.86) for operator 2. Interoperator reliability for both methods was high: correlation coefficients 0.91 (95 % CI, 0.87-0.94) and 0.96 (95 % CI, 0.94-0.97) for manual and semi-automated methods, respectively. Mean NT measured by manual and semi-automated methods was 1.15 mm and 1.28 mm, respectively (P < 0.001). Agreement between the methods was good.

Conclusion

The reliability of semi-automated NT measurements was comparable to that of the manual method. The new method was reproducible and may be used instead of the manual method in the normal range of NT.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700