Characterization of secretomes from a human blood brain barrier endothelial cells in-vitro model after ischemia by stable isotope labeling with aminoacids in cell culture (SILAC)
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- 作者：Victor Llombarta ; victor.llombart.sebastia@vhir.org" class="auth_mail" title="E-mail the corresponding author ; Teresa Garcí ; a-Berrocosoa ; teresa.garcib@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Joan Josep Bech-Serrab ; joanjosepbech@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Alba Simatsa ; alba.simats@vhir.org" class="auth_mail" title="E-mail the corresponding author ; Alejandro Bustamantea ; alebustamanterangel@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Dolors Giralta ; dolors1985@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Gemma Reverter-Branchatb ; greverter@imim.es" class="auth_mail" title="E-mail the corresponding author ; Francesc Canalsb ; fcanals@vhio.net" class="auth_mail" title="E-mail the corresponding author ; Mar Herná ; ndez-Guillamona ; marguillamon@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Joan Montanera ; 31862jmv@comb.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Secretome ; Silac ; Endothelial cells ; Ischemic stroke ; Biomarkers ; Cerebral ischemia ; Blood&ndash ; brain-barrier
- 刊名：Journal of Proteomics
- 出版年：2016
- 出版时间：5 February 2016
- 年：2016
- 卷：133
- 期：Complete
- 页码：100-112
- 全文大小：1268 K
文摘
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Characterization of the secretome of human brain endothelial cells through SILAC
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We identified protein profile changes in the secretome after oxygen and glucose deprivation
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Proteins associated with brain ischemia and potentially involved in blood–brain barrier disruption