Regulation of general amino acid permeases Gap1p, GATA transcription factors Gln3p and Gat1p on 2-phenylethanol biosynthesis via Ehrlich pathway

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• 作者：Xianrui Chen ; Zhaoyue Wang ; ^{wangzy@im.ac.cn} ; ^{wangzhaoyue@126.com} ; Xuena Guo ; Sha Liu ; Xiuping He ; ^{hexp@im.ac.cn}
• 关键词：Saccharomyces cerevisiae ; 2-Phenylethanol ; Ehrlich pathway ; GAP1 ; GLN3 ; GAT1
• 刊名：Journal of Biotechnology
• 出版年：2017
• 出版时间：20 January 2017
• 年：2017
• 卷：242
• 期：Complete
• 页码：83-91
• 全文大小：2642 K
• 卷排序：242

文摘

Gln3p and Gat1p promoted crucial genes of Ehrlich pathway to express and enhanced 2-phenylethanol production significantly. High efficient expression of general amino acid permease Gap1p up-regulated 2-phenylethanol synthesis. Gln3p(2) and Gln3p(58) respectively from diploid and haploid yeast showed different regulation on 2-PE synthesis.