This is the first study to examine effects of LDR on germ cell apoptosis in T2DM rats.
T2DM induced significant increases in germ cell apoptosis and testicular oxidative stress levels relative to control rats.
Repeated exposures to LDR reduced germ cell apoptosis in T2DM.
The protective effects exerted by LDR are associated with increases in Akt and Nrf2 functions.