SAPHO Syndrome Presenting as an Osteolytic Lesion of the Neck

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• 作者：Lourdes Mateo^a ; ^{lmateo.germanstrias@gencat.cat} ; Juana Sanint^a ; Samantha Rodr&iacute ; guez Muguruza^a ; Melania Mart&iacute ; nez Morillo^a ; Ricard Pé ; rez André ; s^b ; Sira Domenech Puigcerver^c
• 关键词：SAPHO ; Psoriatic arthritis ; Osteolytic lesions ; Aseptic osteomyelitis ; Multifocal vertebral osteomyelitis
• 刊名：Reumatología Clínica (English Edition)
• 出版年：2017
• 出版时间：January-February 2017
• 年：2017
• 卷：13
• 期：1
• 页码：44-47
• 全文大小：3839 K
• 卷排序：13

文摘

We report a case of acute-onset multifocal vertebral osteitis with a marked impact on the patient's general health. The radiological, scintigraphic and magnetic resonance findings made it necessary to carry out a differential diagnosis to distinguish it from an infiltrative neoplastic process and determine whether it had an infectious or an inflammatory etiology. The presence of noninfectious multifocal osteitis and sternoclavicular arthritis and the subsequent development of plantar pustulosis pointed to SAPHO syndrome. Treatment with infliximab led to improvement in the clinical symptoms, laboratory values and radiological abnormalities.