刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:29 January 2017
年:2017
卷:483
期:1
页码:305-311
全文大小:919 K
卷排序:483
文摘
RanBPM suppresses the invasiveness of aggressive breast cancer cells by inhibiting BLT2-mediated ROS generation and IL-8 production. The expression levels of RanBPM are reduced in the aggressive breast cancer cells. Restoration of RanBPM levels suppressed the invasiveness of aggressive breast cancer cells in a manner dependent on the LTB4-BLT2 axis.