刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:26 February 2017
年:2017
卷:484
期:1
页码:189-194
全文大小:1398 K
卷排序:484
文摘
MsrA deficiency increases APAP-induced liver damage. MsrA deletion enhances APAP-induced hepatic GSH depletion and oxidative stress. MsrA deficiency induces more profound activation of Nrf2 in response to APAP. MsrA protects the liver from APAP-induced toxicity.