A proposal for a TNM staging system for extramammary Paget disease: Retrospective analysis of 301 patients with invasive primary tumors
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- 作者：Kuniaki Oharaa ; b ; Yasuhiro Fujisawac ; fujisan@md.tsukuba.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Koji Yoshinoa ; Yoshio Kiyoharad ; Takafumi Kadonoe ; Yozo Murataf ; Hisashi Uharag ; Naohito Hattah ; Hiroshi Uchii ; Shigeto Matsushitaj ; Tatsuya Takenouchik ; Toshihiko Hayashil ; Kenichi Yoshimuram ; Manabu Fujimotoc
- 关键词：EMPD ; extramammary Paget disease ; iEMPD ; invasive EMPD ; LN ; lymph node
- 刊名：Journal of Dermatological Science
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：83
- 期：3
- 页码：234-239
- 全文大小：580 K
文摘
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TNM staging system for iEMPD has not yet been established.
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To establish TNM staging system, we retrospectively collected 301 patients with invasive extramammary Paget’s disease.
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51 had distant metastasis and 112 had LN metastasis at diagnosis.
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Distant metastasis, 2 or more lymph node metastases, lymphovascular invasion and tumor thickness over 4 mm correlated with worse survival.
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We propose a TNM staging system for EMPD using simple factors for classification (distant metastasis, LN metastasis and local tumor status).
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Each stage had a statistically distinct survival curve.