A meta-analysis of endoscopic stenting as bridge to surgery versus emergency surgery for left-sided colorectal cancer obstruction

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• 作者：Antonella De Ceglie ; Rosa Filiberti ; Todd H. Baron ; Marcello Ceppi ; Massimo Conio
• 关键词：Stent ; SEMS ; Bridge to surgery ; Emergency surgery ; Obstruction ; Colorectal cancer
• 刊名：Critical Reviews in Oncology/Hematology
• 出版年：2013
• 出版时间：November, 2013
• 年：2013
• 卷：88
• 期：2
• 页码：387-403
• 全文大小：2226 K

文摘

The best approach to resolve colonic obstruction in patients with left-sided colon cancer is not established.

In this meta-analysis the efficacy of stenting as bridge-to-surgery was compared to emergency surgery for the management of left-sided colonic obstruction. Fourteen studies (randomized and non controlled studies) were identified, including 405 patients in the stent group and 471 in the emergency group. The difference between proportions was evaluated as effect size (ES_i). There was large heterogeneity among the studies.

Stenting offered advantages over emergency surgery in terms of increase in primary anastomosis (ES = 25.1 % , p < 0.001), successful primary anastomosis (ES = 23.7 % , p < 0.001), reduction of stoma creation (ES = ?27.1 % , p = 0.03), infections (ES = ?7.9 % , p = 0.006) and other morbidities (ES = ?13.4 % , p < 0.001). The interventions were similar in regards to length of hospitalization, preoperative mortality and long-term survival.