- 作者：Ricardo Andrade Fernades de Mello ; Marcelo Souto Nacif ; Alair Augusto Sarmet M.D. dos Santos ; Ricardo Caldeira Cury ; Carlos Eduardo Rochitte ; Edson Marchiori
- 关键词：Magnetic resonance imaging ; Coronary angiography ; Coronary artery disease
- 刊名：European Journal of Radiology
- 出版年：2012
- 出版时间：August, 2012
- 年：2012
- 卷：81
- 期：8
- 页码：1782-1789
- 全文大小：538 K
Objective
To evaluate the diagnostic performance of stress perfusion cardiac MR (CMR) for detecting significant CAD (¡Ý70 % narrowing) in comparison with invasive coronary angiography (ICA) as a reference standard.Methods
Examinations of 54 patients who underwent both stress perfusion CMR and ICA for investigation of CAD between 2007 and 2009 were evaluated. The CMR protocol included dipyridamole stress and rest perfusion, stress and rest cine MRI for assessment of ventricular function and delayed gadolinium enhancement for assessment of myocardial viability and detection of infarction. CMR interpretation was performed by 2 observers blinded to the results of ICA and the clinical history.
Results
From a total of 54 patients, 37 (68.5 % ) showed significant CAD in 71 coronary territories. A perfusion defect was detected in 35 patients and in 69 coronary territories. Individual stress perfusion CMR evaluation showed the highest accuracy (83 % ) of the CMR techniques. The combined analysis using all sequences increased the overall accuracy of CMR to 87 % .
Conclusion
Combination of perfusion and cine-MR during stress/rest, associated to delayed enhancement in the same protocol improves CMRI diagnostic accuracy and sensitivity for patients with significant coronary stenosis, and may therefore be helpful for risk stratification and defining treatment strategies.