Effects of substance P and Sar-Met-SP, a NK1 agonist, in distinct amygdaloid nuclei on anxiety-like behavior in rats
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- 作者：Gabriel Shimizu Bassia ; b ; Milene Cristina de Carvalhoa ; b ; mccarva@usp.br" class="auth_mail ; mccarvalhorp@gmail.com" class="auth_mail ; Marcus Lira Brandã ; oa ; b
- 关键词：BLA ; basolateral nucleus of the amygdala ; CeA ; central nucleus of the amygdala ; dPAG ; dorsal periaqueductal gray ; EPM ; elevated plus maze ; MeA ; medial nucleus of the amygdala ; NK ; neurokinin receptors ; PAG ; periaqueductal gray ; Sal ; saline ; Sar ; Sar-Met-SP ; SP ; substance P
- 刊名：Neuroscience Letters
- 出版年：21 May 2014
- 年：2014
- 卷：569
- 期：Complete
- 页码：121-125
- 全文大小：1109 K
文摘
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The role of NK1 receptors of the amygdala of rats was investigated in the EPM.
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Injection of SP or Sar into the CeA or MeA, but not the BLA, evoked anxiogenic-like effects.
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Anxiogenic-like effects of the SP in the CeA or MeA are mediated by NK1 receptors.