Recombinant human bone morphogenetic protein 2 (rhBMP-2) immobilized on laser-fabricated 3D scaffolds enhance osteogenesis

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• 作者：Maria Chatzinikolaidou^a ; ^b ; ^{mchatzin@materials.uoc.gr} ; ^{mchatzin@gmail.com} ; Charalampos Pontikoglou^c ; Konstantina Terzaki^b ; Maria Kaliva^a ; ^b ; Athanasia Kalyva^c ; Eleni Papadaki^c ; Maria Vamvakaki^a ; ^b ; Maria Farsari^b
• 关键词：rhBMP-2 ; Hybrid 3D scaffolds ; Bone tissue engineering ; Two-photon polymerization ; Osteogenic differentiation
• 刊名：Colloids and Surfaces B: Biointerfaces
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：149
• 期：Complete
• 页码：233-242
• 全文大小：2104 K
• 卷排序：149

文摘

Direct Laser Writing fabrication of hexagonal hybrid scaffolds of different diagonals. Assessment of the proliferation of bone marrow mesenchymal stem cells. Immobilization of rhBMP-2 on a hybrid material via covalent binding and physical adsorption. Evaluation of the in vitro osteogenic potential of rhBMP-2 immobilized on scaffolds.