- 作者：Luc¨ªa Fern¨¢ndez de Orueta ; Sergio Rodr¨ªguez ¨¢lvarez ; Jorge N¨²?ez Otero ; Mariano G¨®mez Rubio ; Juana Cacho Calvo ; Javier Esteban Fern¨¢ndez
- 关键词：Hipercalcemia ; Tuberculosis esplé ; nica ; Punció ; n aspirativa con aguja fina esplé ; nica ; Reacció ; n en cadena de la polimerasa
- 刊名：Medicina Cl¡§anica
- 出版年：2012
- 出版时间：20 October, 2012
- 年：2012
- 卷：139
- 期：10
- 页码：443-445
- 全文大小：358 K
Background and objective
To describe an unusual clinical presentation as isolated splenic tuberculosis.
Patient and methods
We report a case of isolated splenic tuberculosis, a rare form of extrapulmonary tuberculosis in an immunocompetent patient, and, as a peculiarity, debuts in the form of symptomatic hypercalcemia.
Results
We deeply report the clinical case and the procedures performed to exclude other diseases. We emphasize the usefulness of fine needle aspiration of the spleen to obtain microbiological samples, and the use of specific polymerase chain reaction for mycobacterias to establish the definitive diagnosis of this entity. In agreement with other authors, we chose initial medical treatment with antituberculous drugs, reserving surgery for refractory cases or in case of spontaneous splenic rupture.
Conclusion
Hypercalcemia can be a presentation of granulomatous diseases. The isolated involvement of the spleen by mycobacterias is a rare form of extrapulmonary tuberculosis and more so in immunocompetent patients.