Genetic markers of immunoglobulin G and immunity to cytomegalovirus in patients with breast cancer

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• 作者：Janardan P. Pandey^a ; ^{pandeyj@musc.edu} ; Aryan M. Namboodiri^a ; Sarumathi Mohan^a ; Paul J. Nietert^b ; Lindsay Peterson^c
• 关键词：GM allotypes ; Decoy Fcγ receptor ; Cytomegalovirus ; Immunoevasion
• 刊名：Cellular Immunology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：312
• 期：Complete
• 页码：67-70
• 全文大小：525 K
• 卷排序：312

文摘

CMV RL13-encoded FcγR binds differentially to allotypically disparate IgG. The higher affinity allele (GM 17) is common in people of African descent. These findings may shed light on the racial disparity in breast cancer outcomes.