Platelet function rather than plasmatic coagulation explains hypercoagulable state in cholestatic liver disease
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- 作者：Pihusch ; Rudolf ; Rank ; Andreas ; Gö ; hring ; Peter ; Pihusch ; Markus ; Hiller ; Erhard ; Beuers ; Ulrich
- 关键词：Primary biliary cirrhosis ; Primary sclerosing cholangitis ; Thrombelastography ; Bleeding time ; Flow cytometry
- 刊名：Journal of Hepatology
- 出版年：2002
- 出版时间：November, 2002
- 年：2002
- 卷：37
- 期：5
- 页码：548-555
- 全文大小：176 K
文摘
Background/Aims: As compared to other chronic liver diseases, cholestatic disorders are associated with a better outcome of variceal bleeding and less blood loss at transplantation, suggesting the presence of a hypercoagulable state. We have assessed plasmatic coagulation and platelet function in patients with cholestatic and non-cholestatic liver disease.