Whole-layer and endocardial LS were smaller in LV-segments with FFR < 0.75 than ≥ 0.75.
In logistic regression, whole and endocardial LS predicted segments with FFR < 0.75.
Endocardial LS was slightly positively correlated with FFR (R = 0.299, P = 0.044).
Best cutoff value of whole-layer LS was 14.0% to detect LV-segments with FFR < 0.75.
Best cutoff value of endocardial LS was 10.0% to detect LV-segments with FFR < 0.75.