Distinct requirements of wls, wnt9a, wnt5b and gpc4 in regulating chondrocyte maturation and timing of endochondral ossification

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• 作者：Irving TC Ling^a ; ^c ; Lucie Rochard^a ; Eric C. Liao^a ; ^b ; ^{cliao@partners.org}
• 关键词：Wnt ; Chondrocyte ; Osteoblast ; Zebrafish ; Meckel's cartilage ; Endochondral ossification
• 刊名：Developmental Biology
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：421
• 期：2
• 页码：219-232
• 全文大小：2371 K
• 卷排序：421

文摘

Non-canonical Wnt signaling is required for craniofacial development. Two distinct chondrocyte populations in Meckel's cartilage with different sensitivity to Wnt signaling. Non-canonical Wnt signaling is required to align, polarize and orient cells in regions fated to become endochondral bone.