Myeloid derived suppressor cells in inflammatory conditions of the central nervous system
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- 作者：Carolina Melero-Jereza ; Marí ; a Cristina Ortegaa ; b ; Veró ; nica Moliné ; -Velá ; zquezc ; Diego Clementea ; dclemente@sescam.jccm.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Multiple sclerosis ; Spinal cord injury ; Autoimmunity ; Neuroregeneration ; Cell therapy ; T cell suppression
- 刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：1862
- 期：3
- 页码：368-380
- 全文大小：1647 K
文摘
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MDSCs are immature myeloid cells with T cell suppressive activity.
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Compilation of MDSC roles in several neuroimmune diseases is depicted.
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MDSCs are positive elements for the control of EAE progression.
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An overview of the putative therapeutical use of MDSCs in neuroimmune diseases.