The Effect of Bone Marrow Plasma Cell Burden on Survival in Patients with Light Chain Amyloidosis Undergoing High-Dose Melphalan and Autologous Stem Cell Transplantation
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- 作者：Christopher Dittus1 ; Nsabimana Uwumugambi2 ; Fangui Sun3 ; J. Mark Sloan1 ; Vaishali Sanchorawala1 ; vaishali.sanchorawala@bmc.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：Plasma cells ; Light chain (AL) amyloidosis ; Survival ; Melphalan ; Stem cell transplantation
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：22
- 期：9
- 页码：1729-1732
- 全文大小：508 K
文摘
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Overall survival of patients with light chain amyloidosis and bone marrow plasma cell burden ≤ 10% and >10% did not differ after high-dose melphalan and stem cell transplantation
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Induction therapy for patients with bone marrow plasma cell burden > 10% and < 30% did not alter overall survival
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Hematologic complete response and relapse rates did not differ in patients with bone marrow plasma cell burden ≤ 10% and >10% after high-dose melphalan and stem cell transplantation.