Effects of memantine added to risperidone on the symptoms of schizophrenia: A randomized double-blind, placebo-controlled clinical trial

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• 作者：Robabeh Mazinani^a ; ^{robabeh_mazinani@yahoo.com} ; Somayeh Nejati^a ; ^b ; ^{so.nejati@uswr.ac.ir} ; Mohammadreza Khodaei^a
• 关键词：Memantine ; Positive and negative symptoms ; Cognitive function
• 刊名：Psychiatry Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：247
• 期：Complete
• 页码：291-295
• 全文大小：271 K
• 卷排序：247

文摘

Antipsychotics have been helpful in improving negative symptoms of schizophrenia Understanding the role of neurotransmitters in the pathogenesis of schizophrenia has led to the development of new drugs Memantine can significantly improve negative and cognitive symptoms among patients with schizophrenia Adjunct treatment with NMDA receptor antagonists can be considered as a useful addition to standard care in the future