Mespaa can potently induce cardiac fates in zebrafish
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- 作者：Ashish R. Deshwara ; b ; John C. Onderisina ; b ; Anastasiia Aleksandrovaa ; Xuefei Yuana ; b ; Jeffrey T.A. Burrowsa ; Ian C. Scotta ; b ; c ; ian.scott@sickkids.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mesp1 ; Mesps ; Gata5 ; Cardiac progenitors ; Cardiac specification ; Mesoderm ; Zebrafish ; Cell migration ; Left-right asymmetry ; Cardiac looping
- 刊名：Developmental Biology
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：418
- 期：1
- 页码：17-27
- 全文大小：7604 K
文摘
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Mespaa potently programs non-cardiogenic cells to a cardiac fate in zebrafish.
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Mespaa acts via Gata5/6 during cardiac reprogramming.
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Surprisingly, Mespaa is not required for cardiac development.
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Mespaa and other Mesps are required for proper cardiac laterality in zebrafish.