Reciprocal relationship between membrane type 1 matrix metalloproteinase and the algesic peptides of myelin basic protein contributes to chronic neuropathic pain
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文摘
MT1-MMP generates the algesic MBP peptides in vitro and the damaged PNS. The algesic MBP induces MT1-MMP expression in the PNS. Short-term MT1-MMP blockade attenuates allodynia and the algesic MBP release.

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