Current organ allocation disadvantages kidney alone recipients over combined organ recipients

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• 作者：Michael S. Martin ; M.D.^a ; Michael E. Hagan ; D.O.^b ; Darla K. Granger ; M.D.^a ; ^{darla.granger@stjohn.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Kidney transplant ; Allocation ; KDPI
• 刊名：The American Journal of Surgery
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：211
• 期：3
• 页码：525-528
• 全文大小：357 K

文摘

The United Network for Organ Sharing began including the Kidney Donor Profile Index (KDPI) March 26, 2012 and began a new allocation scheme December 1, 2014.

Methods

Kidney donors from our organ procurement organization from March 2012 to December 2014 were reviewed. The KDPIs of all 919 kidney only transplants were compared with all 102 kidney/extrarenal transplants.

Results

The average KDPI for kidney alone allografts was 47 (range 1 to 100) (standard deviation = 25.83) vs 27 for kidney/extrarenal kidneys (range 1 to 82) (standard deviation = 20.16) (P < .001, t test). Multivariate analysis including in- vs out-of-state recipient, donor body mass index, and donation after cardiac death vs brain-dead donor showed significantly lower KDPI for kidney/extrarenal transplants.

Conclusions

Kidney/extrarenal organs have decreased graft survival compared with kidneys transplanted alone. In this sample, 21% of lower KDPI kidneys were allocated as kidney/extrarenal organs. This disadvantages those waiting for a kidney alone. Attention to the outcomes of kidneys transplanted with extrarenal organs is needed.