Synthesis and evaluation of a novel fluorescent chemosensor for glutathione based on a rhodamine B and N-[4-(carbonyl) phenyl]maleimide conjugate and its application in living cell imaging
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- 作者：Hai Shua ; Xiaolei Wua ; Baojing Zhouc ; Yingbin Hanc ; Mingjie Jina ; Jing Zhub ; zhujing1227@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Xiaofeng Baoa ; baoxiaofeng@mail.njust.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Rhodamine B ; Colorimetric fluorescent probe ; GSH ; Cell imaging
- 刊名：Dyes and Pigments
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：136
- 期：Complete
- 页码：535-542
- 全文大小：2320 K
文摘
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A new rhodamine B derivatized chemosensor (L1) was synthesized and characterized.
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The interactions of L1 with amino acids and metal ions were studied.
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L1 exhibited a highly sensitive and selective fluorescence response toward GSH.
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The detection limit of GSH by L1 was 0.219 μM.
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L1 can be used as a fluorescent probe for the detection of GSH in living cells.