Motor cortical plasticity in extrinsic hand muscles is determined by the resting thresholds of overlapping representations
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- 作者：J.L. Mirdamadi ; L.Y. Suzuki ; S.K. Meehan ; skmeehan@umich.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：theta burst stimulation ; transcranial magnetic stimulation ; plasticity ; motor cortex ; flexor carpi radialis ; contraction
- 刊名：Neuroscience
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：333
- 期：Complete
- 页码：132-139
- 全文大小：769 K
文摘
For extrinsic hand muscles, agonist–antagonist resting thresholds predict the nature of cTBS induced plasticity.
Individuals with similar FCR-ECR resting thresholds demonstrated the expected post-cTBS suppression of FCR excitability.
Individuals with larger resting thresholds disparities showed less suppression and even enhancement of FCR MEPs post-cTBS.
Concurrent contraction with cTBS consistently suppressed ECR cortical excitability regardless of resting thresholds.
Resting state interactions need to be accounted for when predicting intervention outcomes in motor cortex.