Antimicrobial resistance islands: resistance gene clusters in Salmonella chromosome and plasmids

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• 作者：Vivi Miriagou ; Alessandra Carattoli and Sé ; amus Fanning
• 关键词：Antimicrobial resistance ; Horizontal genetic transfer ; Insertion sequence ; Integron ; Mobile genetic element ; Plasmid ; Resistance gene ; Salmonella ; Transposon
• 刊名：Microbes and Infection
• 出版年：2006
• 出版时间：June 2006
• 年：2006
• 卷：8
• 期：7
• 页码：1923-1930
• 全文大小：351 K

文摘

Genes conferring simultaneous resistance to different classes of antimicrobials, confer a selective advantage to the host, particularly when those corresponding antibiotics are administered. Multiple resistance genes clustered within the same genetic locus (resistance island) can be transferred en bloc to other organisms. In this chapter we review novel multidrug resistance islands recently described in Salmonella.