Research on vaccines during pregnancy: Reference values for vital signs and laboratory assessments
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- 作者：Jeanne S. Sheffield ; Flor M. Munoz ; Richard H. Beigi ; Sonja A. Rasmussen ; Kathryn M. Edwards ; Jennifer S. Read ; R. Phillips Heine ; Kevin A. Ault ; Geeta K. Swamy ; Indira Jevaji ; Catherine Y. Spong ; Kimberly B. Fortner ; Shital M. Patel ; Mirjana Nesin
- 关键词：Laboratory assessment ; Toxicity grading scale ; Maternal immunization
- 刊名：Vaccine
- 出版年：2013
- 出版时间：13 September, 2013
- 年：2013
- 卷：31
- 期：40
- 页码：4264-4273
- 全文大小：320 K
文摘
The Division of Microbiology and Infectious Diseases at the National Institute of Allergy and Infectious Diseases, National Institutes of Health organized a series of conferences, ¡°Enrolling Pregnant Women in Clinical Trials of Vaccines and Therapeutics¡±, to discuss enrollment and safety assessments of pregnant women in clinical trials of vaccines. Experts in obstetrics, maternal-fetal medicine, infectious diseases, pediatrics, neonatology, genetics, vaccinology and clinical trial design were charged with identifying normal ranges for vital signs and laboratory assessments in pregnancy. A grading system for adverse events was then developed