刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
出版时间:January 2017
年:2017
卷:165
期:part_PB
页码:421-429
全文大小:1350 K
卷排序:165
文摘
Progesterone attenuates experimental autoimmune encephalomyelitis (EAE) severity in mice. EAE mice showed altered mRNA levels of steroidogenic proteins in the spinal cord. Progesterone restores mRNA levels of neurosteroidogenic proteins and enzymes. Enhanced neurosteroidogenesis may reinforce the effects of exogenous progesterone.