The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3
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- 作者：Seong Min Lee ; smlee4@wisc.edu" class="auth_mail" title="E-mail the corresponding author ; J. Wesley Pike
- 关键词：VDR ; vitamin D receptor ; 1 ; 25(OH)2D3 ; 1 ; 25-dihydroxyvitamin D3 ; PTG ; parathyroid gland ; PTH ; parathyroid hormone ; RXR ; retinoid X receptor ; VDRE ; vitamin D response element ; ChIP-seq ; ChIP-sequencing ; RNA-seq ; RNA-sequencing ; HVDRR ; hereditary 1 ; 25-dihydroxyvitamin D resistant rickets ; VDDR-1 ; vitamin D dependency rickets type 1 ; BAC ; bacterial artificial chromosome ; qPCR ; quantitative polymerase chain reaction
- 刊名：Journal of Steroid Biochemistry and Molecular Biology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：164
- 期：Complete
- 页码：265-270
- 全文大小：507 K
文摘
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The VDR de-represses PTH secretion in the absence of 1,25(OH)2D3.
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The VDR is involved in bone metabolism in the absence of 1,25(OH)2D3.
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The VDR modulates expression of its target genes in the absence of 1,25(OH)2D3.