One hundred extracted single-rooted human teeth were divided into 4 experimental groups and 2 positive and negative control groups. EDTA was used in groups 1 and 2. In groups 3 and 4 MTAD was used. The root canals were then obturated with gutta-percha/AH-Plus in groups 1 and 3 and Resilon/Epiphany (SE) in groups 2 and 4. After sterilization, the samples were coronally exposed to human saliva and monitored every 24 hours for 60 days.
In groups 1, 2, 3, and 4, 45 % , 65 % , 90 % , and 65 % of specimens leaked within 60 days, respectively. There were statistically significant differences between group 1 and 3 (P < .05).
Resilon/Epiphany (SE) system is as effective as gutta-percha/AH-Plus in preventing saliva leakage. MTAD did not adversely affect the sealing ability of Resilon/Epiphany (SE).