Chlorogenic acid ameliorated concanavalin A-induced hepatitis by suppression of Toll-like receptor 4 signaling in mice

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• 作者：Yinglin Yuan^a ; ¹ ; Xia Gong^b ; ¹ ; Li Zhang^c ; Rong Jiang^c ; Junxia Yang^a ; Bin Wang^d ; Jingyuan Wan^a ; ^{jywan@cqmu.edu.cn}
• 关键词：Chlorogenic acid ; Concanavalin A ; Hepatitis ; Adhesion molecules ; Leukocytes ; Toll-like receptor 4
• 刊名：International Immunopharmacology
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：44
• 期：Complete
• 页码：97-104
• 全文大小：1566 K
• 卷排序：44

文摘

Chlorogenic acid protects from Con A-induced liver injury. Chlorogenic acid inhibits Con A-primed hepatic leukocytes infiltration. Chlorogenic acid downregulates expression of hepatic adhesion molecules induced by Con A. Chlorogenic acid suppresses TLR4 signal activation elicited by Con A.